Otto Octavius, I.C. Dr. Octopus, one of Spider-Man's deadliest adversaries, has become even deadlier! Relying on his vast scientific knowledge, Doc Oc combined his own DNA with that of a ferocious octopus, mutating him into an incredibly powerful creature. Armed with real tentacles and his Octo-Craft which is [sic] can ensnare Spider-Man, Dr. Octopus has truly become the Ultimate Octopus!