Learning of the appearnace of the Lizard and the mutated Man-Spider creature in New York through the local media, Kraven decides a hunt of these monsters would be the ultimate hunt ineed. Taking his weapons in hand and using his amazing tracking skills, Kraven soon closes in on the creatures. Cornering the Man-Spider only to be attacked himself, Kraven and the creature go into battle! But this is no ordinary prey, as Kraven quickly learns-this is a mutated monster who possesses the power and the instincts of a spider and a human being!